The integration host factor-DNA complex upstream of the early promoter of bacteriophage Mu is functionally symmetric.

نویسندگان

  • P van Ulsen
  • M Hillebrand
  • L Zulianello
  • P van de Putte
  • N Goosen
چکیده

Inversion of the ihf site in the promoter region of the early promoter of bacteriophage Mu did not influence the integration host factor (IHF)-mediated functions. IHF bound to this inverted site could counteract H-NS-mediated repression, directly activate transcription, and support lytic growth of bacteriophage Mu. This implies that the IHF heterodimer and its asymmetrical binding site form a functionally symmetrical complex.

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عنوان ژورنال:
  • Journal of bacteriology

دوره 179 9  شماره 

صفحات  -

تاریخ انتشار 1997